Multiple System Atrophy

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Multiple System Atrophy  

What is Multiple System Atrophy? (NINDS information)
 

Multiple system atrophy (MSA) is the current name for disorders once known individually as striatonigral degeneration, sporadic olivopontocerebellar atrophy, and the Shy-Drager syndrome.  MSA is a progressive neurodegenerative disorder characterized by symptoms of autonomic nervous system failure (such as lightheadedness or fainting spells, constipation, erectile failure in men, and urinary retention) combined with tremor and rigidity, slurred speech, or loss of muscle coordination.  MSA affects both men and women, primarily in their 50s.  It can progress swiftly or slowly, but people with MSA generally survive for 9 years after the appearance of symptoms.  There is no remission from the disease.

 

Is there any treatment?
 

There is no specific treatment for nerve degeneration in MSA. Levodopa, used to treat rigidity and tremor in Parkinson's disease, may offer some help. However, striatonigral degeneration does not respond well to levodopa. Dopamine and anticholinergic drugs may be prescribed to treat spasms. Orthostatic hypotension may be treated with flucortisone and other drugs that raise blood pressure. Increased dietary fiber intake or use of laxatives may relieve constipation, and drugs or a penile implant may help with male impotence. A routine of stretching and exercise can help retain muscle strength and range of movement. An artificial feeding tube or breathing tube may be surgically inserted for management of swallowing and breathing difficulties.

What is the prognosis?
 

MSA is a progressive disorder and most patients have a life expectancy after diagnosis of about 10 years or less.

 


More Resources About: Multiple System Atrophy

Shy Drager Syndrome Review

What is Shy dragger syndrome? It is a disease first described by Dr. Milton Shy and Dr. Glen Dragger in 1960 It is a rare disease of unknown etiology that causes a progressive degeneration of the central and autonomic nervous system. It is characterized by the the following symptoms: Parkinson like tremor Orthostatic hypotension Erectile dysfunction Fecal and urinary Incontinence Alterations of muscle tone (stiffness) Anhidrosis Progressive dementia Need more information on Shy Dragger disease?

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Multiple system atrophy
... Multiple system atrophy is a degenerative disorder characterized by the following ... Causes, incidence, and risk factors: Multiple system atrophy (MSA) is a rare degenerative condition ...


WE MOVE - Multiple System Atrophy
Multiple system atrophy (MSA) is a neurodegenerative disease marked by a combination of symptoms affecting movement, blood pressure, and other body functions; hence the label multiple system atrophy. The cause of MSA is unknown. ... Multiple System Atrophy. " Multiple System Atrophy Information for Patients and Caregivers (see table of contents ... Multiple System Atrophy Information for Patients and Caregivers ...


Multiple System Atrophy Horacio Kaufmann
... 1. Multiple System Atrophy. Horacio Kaufmann. Although the precise definition of multiple. system atrophy (MSA) has been difficult, a ...


eMedicine - Multiple System Atrophy : Article by André Diedrich, MD, PhD
... and related keywords: MSA, multiple-system atrophy, multisystem atrophy, Shy-Drager syndrome, striatonigral ... Yasuda T, et al: Cerebral atrophy in multiple system atrophy by MRI ...


NORD - National Organization for Rare Disorders, Inc.
... General Discussion. Multiple system atrophy (MSA) is a rare progressive neurological disorder characterized by a varying ... The exact cause of multiple system atrophy is unknown ...


Multiple System Atrophy with Orthostatic Hypotension Information Page: National Institute of Neurological Disorders ...
Multiple System Atrophy with Orthostatic Hypotension information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ... What is Multiple System Atrophy with Orthostatic Hypotension? Multiple system atrophy with orthostatic ...


MSA
... Shy-Drager Syndrome" this complex syndrome is currently referred to as "Multiple System Atrophy" or MSA ... those affected with MSA. Multiple system atrophy is associated with both upper ...


ClinicalTrials.gov - Information on Clinical Trials and Human Research Studies: Trial List
... Search results for Multiple System Atrophy [ALL-FIELDS] are shown below ... Disease; Atypical Parkinson Syndromes; Multiple System Atrophy; Progressive Supranuclear Paralysis; Essential ...


MedlinePlus Medical Encyclopedia: Multiple system atrophy
Medical Encyclopedia. Multiple system atrophy. Contents of this page: Illustrations. Shy-Drager syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome ... Multiple system atrophy is a degenerative disorder characterized by the following ... Multiple system atrophy (MSA) is a rare degenerative condition ...


Multiple system atrophy
... Multiple system atrophy. Central nervous system. Definition: Multiple system atrophy is a degenerative disorder ... factors: Multiple system atrophy (MSA) is a rare degenerative condition ...


Multiple System Atrophy Information Page: National Institute of Neurological Disorders and Stroke (NINDS)
Information sheet on Multiple System Atrophy compiled by NINDS. ... What is Multiple System Atrophy? Multiple system atrophy (MSA) refers to three ... by their foremost symptoms: olivopontocerebellar atrophy (OPCA), which primarily affects balance ...



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The Parkinson's Institute Movement Disorders
... People with Multiple System Atrophy (MSA) can exhibit a wide variety of symptoms, including: postural instability ... As the term "multiple system atrophy" implies, MSA can vary in its ...


Symptoms of Multiple System Atrophy
Multiple System Atrophy. Symptoms of Multiple System Atrophy. Symptoms of the disorder include: Parkinsonism (tremors, muscle rigidity) Cerebellar or corticospinal signs (balance and movement difficulties) ... Mayo Clinic Medical Services Multiple System Atrophy. Multiple System Atrophy ... Multiple system atrophy occurs twice as often in men as women and is usually diagnosed in people in ...

Multiple System Atrophy
... Multiple System Atrophy (MSA) Timothy C. Hain, MD -- Northwestern University Medical School ... Multiple system atrophy is a rare neurological disorder characterized by a combination ...


Multiple System Atrophy
Article describes multiple system atrophy, its symptoms, diagnosis, and treatment. ... Multiple system atrophy (MSA) is a disorder in which multiple parts of the nervous system ... nerve cells in multiple system atrophy is not known. Multiple system atrophy is estimated ...


Multiple System Atrophy (MSA) treatment at Mayo Clinic.
Treatment for multiple system atrophy (MSA), a Parkinson's plus syndrome, at Mayo Clinic. ... Multiple system atrophy (MSA), one of several Parkinson's plus syndromes, is a rare ... Patients with multiple system atrophy eventually develop symptoms of both Parkinson's disease ...
 

Multiple system atrophy
Multiple system atrophy. Alternative Names: Shy-Drager syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson's plus syndrome. Treatment: There is no cure for MSA, and there is no known means to slow progression. ... Toggle: English / Spanish. Multiple system atrophy. Overview. Symptoms. Treatment ...


Autonomic Disorders Research and Treatment Program - Department of Neurology - Mount Sinai School of Medicine
The Autonomic Nervous System Laboratory is the hub of the Department of Neurology's research efforts into autonomic disorders. ... Multiple System Atrophy. Multiple system atrophy is a neurological disorder that begins in ... disease, in patients with Multiple System Atrophy, treatment with L-Dopa or dopaminergic ...


MDVU Resource Library - Multiple System Atrophy
Multiple system atrophy or MSA is a neurodegenerative disease marked by a combination of symptoms affecting movement, blood pressure, and other body functions. ... body functions; hence the label "multiple system" atrophy. The cause of MSA ...

Multiple system atrophy - Wikipedia, the free encyclopedia
Multiple system atrophy. From Wikipedia, the free encyclopedia. Multiple system atrophy (MSA) is a degenerative neurological disorder characterized by a combination of the following: