During an MS attack, inflammation occurs in areas of
the white matter* of the central nervous
system in random patches called plaques. This
process is followed by destruction of myelin,
the fatty covering that insulates nerve cell fibers
in the brain and spinal cord. Myelin facilitates the
smooth, high-speed transmission of electrochemical
messages between the brain, the spinal cord, and the
rest of the body; when it is damaged, neurological
transmission of messages may be slowed or blocked
completely, leading to diminished or lost function.
The name "multiple sclerosis" signifies both the
number (multiple) and condition (sclerosis, from the
Greek term for scarring or hardening) of the
demyelinated areas in the central nervous system.
National Institute of Neurological
Disorders and Stroke (NINDS)
National Institutes of Health
Brain Resources and Information Network
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