After migraine, the most common type of vascular
headache is the toxic headache produced by fever.
Pneumonia, measles, mumps, and tonsillitis are among
the diseases that can cause severe toxic vascular
headaches. Toxic headaches can also result from the
presence of foreign chemicals in the body. Other
kinds of vascular headaches include "clusters,"
which cause repeated episodes of intense pain, and
headaches resulting from a rise in blood pressure.
Chemical culprits. Repeated
exposure to nitrite compounds can result in a dull,
pounding headache that may be accompanied by a
flushed face. Nitrite, which dilates blood vessels,
is found in such products as heart medicine and
dynamite, but is also used as a chemical to preserve
meat. Hot dogs and other processed meats containing
sodium nitrite can cause headaches.
Eating foods prepared with monosodium glutamate
(MSG) can result in headache. Soy sauce, meat
tenderizer, and a variety of packaged foods contain
this chemical which is touted as a flavor enhancer.
Headache can also result from exposure to poisons,
even common household varieties like insecticides,
carbon tetrachloride, and lead. Children who ingest
flakes of lead paint may develop headaches. So may
anyone who has contact with lead batteries or lead-glazed
pottery.
Artists and industrial workers may experience
headaches after exposure to materials that contain
chemical solvents. These solvents, like benzene, are
found in turpentine, spray adhesives, rubber cement,
and inks.
Drugs such as amphetamines can cause headaches as
a side effect. Another type of drug-related headache
occurs during withdrawal from long-term therapy with
the antimigraine drug ergotamine tartrate.
Jokes are often made about alcohol hangovers but
the headache associated with "the morning after" is
no laughing matter. Fortunately, there are several
suggested treatments for the pain. The hangover
headache may also be reduced by taking honey, which
speeds alcohol metabolism, or caffeine, a
constrictor of dilated arteries. Caffeine, however,
can cause headaches as well as cure them. Heavy
coffee drinkers often get headaches when they try to
break the caffeine habit.
Cluster headaches.
Cluster headaches are a rare form of headache
notable for their extreme pain and their pattern of
occurring in "clusters", usually at the same time(s)
of the day for several weeks. A cluster headache
usually begins suddenly with excruciating pain on
one side of the head, often behind or around one
eye. In some individuals, it may be preceded by a
migraine-like "aura." The pain usually peaks over
the next 5 to 10 minutes, and then continues at that
intensity for up to an hour or two before going
away.
People with cluster headaches describe the pain
as piercing and unbearable. The nose and the eye on
the affected side of the face may also get red,
swollen, and runny, and some people will experience
nausea, restlessness and agitation, or sensitivities
to light, sound, or smell. Most affected individuals
have one to three cluster headaches a day and two
cluster periods a year, separated by periods of
freedom from symptoms.
A small group of people develop a chronic form of
the disorder, characterized by bouts of cluster
headaches that can go on for years with only brief
periods (2 weeks or less) of remission.
Cluster headaches generally begin between the
ages of 20 and 50, although the syndrome can also
start in childhood or late in life. Males are much
more likely than females to develop cluster
headaches. Alcohol (especially red wine) provokes
attacks in more than half of those with cluster
headaches, but has no effect once the cluster period
ends. Cluster headaches are also strongly associated
with cigarette smoking.
Scientists aren't sure what causes the disorder.
The tendency of cluster headaches to occur during
the same time(s) from day to day, and more often at
night than during the daylight hours, suggests they
could be caused by irregularities in the body’s
circadian rhythms, which are controlled by the brain
and a family of hormones that regulate the
sleep-wake cycle.
There are medications available to lessen the
pain of a cluster headache and suppress future
attacks. Oxygen inhalation and triptan drugs (such
as those used to treat migraine) administered as a
tablet, nasal spray, or injection can provide quick
relief from acute cluster headache pain. Lidocaine
nasal spray, which numbs the nose and nostrils, may
also be effective. Ergotamine and corticosteroids
such as prednisone and dexamethasone may be
prescribed to break the cluster cycle and then
tapered off once headaches end. Verapamil may be
used preventively to decrease the frequency and pain
level of attacks. Lithium, valproic acid, and
topiramate are sometimes also used preventively.
Painful pressure . Chronic high
blood pressure can cause headache, as can rapid
rises in blood pressure like those experienced
during anger, vigorous exercise, or sexual
excitement.
The severe "orgasmic headache" occurs right
before orgasm and is believed to be a vascular
headache. Since sudden rupture of a cerebral blood
vessel can occur, this type of headache should be
evaluated by a doctor.
National Institute of Neurological
Disorders and Stroke (NINDS)
National Institutes of Health
Brain Resources and Information Network
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