As we advance in the knowledge of controlling and curing
diseases and medical conditions more people achieve longer lives. Thus
prevalence of diseases and conditions "related" to aging rises dramatically. One
of this rising problems is Dementia.
Dementia is a syndrome (a disease or condition that has
many etiologies) that courses with progressive and "disabling" cognitive
impairment. The keyword that describes best this condition is disabling, because
it is usual that the elderly will lose some of their cognitive abilities but
never to the point of not being able to conduct their social and occupational
activities and care for themselves. Once a person reaches the stage that their
normal daily activities are impaired, then he or she becomes a burden to his or
her family, and also a social and economic burden.
Diagnostic criteria for dementia (DSM-IV):
Short- and long-term memory impairment
Impairment in abstract thinking, judgment, other higher cortical function or
personality change
Cognitive disturbance interferes with significantly with work, social
activities or relationships with others
These cognitive changes do not occur exclusively in the setting of delirium
By using this criteria we can classify people in three groups:
Cognitively normal
Demented
Mild cognitive impairment
Mild cognitive impairment is best explained as any cognitive impairment of a
single domain (usually memory impairment below 1.5 standard deviations) that
does not affect their daily social and occupational activities. Since dementia
requires at least two domains (memory and a second domain) of cognitive
impairment, these people cannot be classified as demented.
Alzheimer's disease:
It is a form of late onset dementia and one of the most
common causes of dementia. Diagnostic criteria for Alzheimer's disease (NINCDS/ADRDA):
A. Alzheimer's disease is characterized by progressive decline and ultimately
loss of multiple cognitive functions, including both:
Memory impairment--impaired ability to learn new information or to recall
previously learned information.
And at least one of the following:
Loss of word comprehension ability, for example, inability to respond to "Your
daughter is on the phone." (aphasia);
Loss of ability to perform complex tasks involving muscle coordination, for
example, bathing or dressing (apraxia);
Loss of ability to recognize and use familiar objects, for example, clothing
(agnosia);
Loss of ability to plan, organize, and execute normal activities, for
example, going shopping.
B. The problems in "A" represent a substantial decline from previous
abilities and cause significant problems in everyday functioning.
C. The problems in "A" begin slowly and gradually become more severe.
D. The problems in "A" are not due to:
Other conditions that cause progressive cognitive decline, among them:
stroke, Parkinson's disease, Huntington's chorea, brain tumor, etc.
Other conditions that cause dementia, among them: hypothyroidism, HIV
infection, syphilis, and deficiencies in niacin, vitamin B12, and folic acid.
E. The problems in "A" are not caused by episodes of delirium.
F. The problems in "A" are not caused by another mental illness: depression,
schizophrenia, etc.